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3. Please comment about this case of a 76-year-old patient with permanent atrial fibrillation and hypertension, who had a prolonged activated partial thromboplastin time (APTT) with the use of dabigatran 110 mg twice-a-day.
3. 영구적인 심방 세동과 고혈압이 있으며, 활성화 부분 트롬보플라스틴 시간(APTT)이 길며 1일 2회 다비가트란을 110 mg 복용하는 76세 환자의 사례에 대해 의견을 제시해 주십시오.
3. Hãy đưa ra ý kiến về trường hợp một bệnh nhân 76 tuổi mắc chứng rung nhĩ mãn tính và huyết áp cao có thời gian tromboplastin cục bộ kéo dài (APTT) sử dụng thuốc dabigatran 110mg hai lần một ngày.
3. Silakan berkomentar pada kasus ini, yaitu seorang pasien berumur 76 tahun dengan atrial fibrilasi dan hipertensi permanen, yang memililiki waktu tromboplastin parsial yang diaktifkan (APTT) dengan penggunaan dabigatran 110 mg dua hari sekali.
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Department of Neurology, Asan Medical Center,
University of Ulsan, Republic of Korea
The Zena and Michael A. Wiener Cardiovascular
Institute, Icahn School of Medicine at Mount Sinai, USA
Dr. Raymond Wong is Honorary Clinical Associate Professor and Head of the Division of Haematology at the Department of Medicine & Therapeutics of the Chinese University of Hong Kong. He is also Consultant in the Department of Medicine and Therapeutics at the Prince of Wales Hospital, Hong Kong.
Ganesananthan Shanmuganathan is currently Consultant Physician and Gastroenterologist at Pantai Hospital Kuala Lumpur, Bangsar, Kuala Lumpur.
Kenneth Butcher is an Associate Professor of Neurology at the University of Alberta. He completed his PhD concurrently with his MD at the University of Western Ontario. His thesis was based on the autonomic effects of stroke. Following his Neurology residency at the University of Alberta, Dr. Butcher travelled to Australia where he completed a post-doctoral fellowship in magnetic resonance imaging (MRI) and advanced computed tomography (CT) imaging of acute stroke. In 2006, he returned to Alberta and took up his current faculty position. His major clinical and research interests are in acute stroke care. He recently designed and led a multicentre, randomised, trial of blood pressure reduction in acute intracerebral haemorrhage patients.